By M. Ian Phillips (auth.), M. Ian Phillips PhD, DSc (eds.)
Announcement of the full sequencing of the human genome in April 2003 validated the presence of millions of goals for antisense oligonucleotides and opened the best way to thousands of preclinical animal experiences and a few 20 ongoing scientific trials. during this moment variation of Antisense Therapeutics, a workforce of major researchers and scientific scientists show the recent fact of antisense and RNA inhibition for treating a huge variety of ailments. The authors exhibit how antisense oligonucleotides are being designed and studied relating to high blood pressure, a variety of cancers, inflammatory bowel sickness, mind issues, the blood-brain barrier, and drug supply. Highlights comprise RNA-based treatments for lots of ailments, up to date tools and functions, and perception into the big capability to supply a brand new iteration of gear.
hugely sensible and affliction orientated, Antisense Therapeutics, moment variation bargains not just a primer for a brand new iteration of drug discovery researchers, but additionally an illuminating exploration of the capability in exploiting RNA inhibition for novel human therapeutics.
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